A collection of letters, legal papers and financial records of three generations of the prominent Philadelphia family. Spanning 1745-1955, detailed are the legal cases and political advocacy work of John Kintzing Kane (1795-1858), Robert Patterson Kane (1827-1906), and Francis Fisher Kane (1866-1955). Also includes correspondence, architectural drawings, and photograph albums of the Cope family. Robert Patterson Kane's daughter Eliza Middleton Kane (1863-1952) married the Philadelphia architect Walter Cope (1860-1902) in 1893. The APS papers of Elisha Kent Kane are in call no. B K132.

The collection of about 850 items covers the period from 1782 to c. 1936, with the bulk dating to the 1780s to 1840s. The collection is divided into four series. Series I contains correspondence relating to a wide variety of topics, including French and English politics, business, trade, religious matters, and personal affairs. Many of the items are letters of introduction. There is also information on John Vaughan's immigration to America, Joseph Priestley, vaccines and inoculation (with Jefferson's comments on the same), Vaughan's business in Philadelphia, and the American Philosophical Society. Also included in this series are 2 boxes with copies of Vaughan correspondence as well as miscellaneous notes by E. W. Madeira, gathered in the course of his research on Vaughan in the 1930s. Series II consists of three volumes. Included are two of Vaughan's commonplace books. One, entitled, "J. Vaughan's book," May 17, 1779 (47 pp., in Latin; 870/L34), includes mostly Latin notations. The other commonplace book, dated 1783 (ca. 66 pp.; B V 462.c), includes comments on several prominent Americans, such as Benjamin Rush and David Rittenhouse, as well as American society generally. The third volume is a copybook with thirty letters spanning the period 1784 to 1801 (B V462.1). Series III includes material relating to Vaughan's administration of the estate of the Philadelphia merchant Samuel Merrick, 1796-1822 (Vaughan-Merrick Papers, B V462.m; 2 boxes). Series IV consists of correspondence between Vaughan and the DuPont Co. for which he served as agent (B V462.4; photocopies of 73 letters).

After a brief career in the Congregational church, J. Peter Lesley (1819-1903) left the ministry in 1852 to work full-time as a geologist. Having gained experience in structural geology and stratigraphy with the First Pennsylvania Geological Survey (1836-1842), Lesley became an expert in the geology of coal, working for the Pennsylvania Railroad and other corporations and conducting some of the first systematic studies of the state's hydrocarbon resources. A long-time professor at the University of Pennsylvania, he was elected to the APS in 1856, serving variously as its librarian, secretary, and vice president, and he was selected as Director of the Second Pennsylvania Geological Survey (1875-1889). The Lesley Papers include letters to and from Peter Lesley and his wife, Susan on geology, coal and iron mining, abolition, educational reform, organized charity, and Unitarianism. The collection offers important insight into academic and applied geology in late 19th century Pennsylvania, the development of the coal and iron industries, as well as into the Lesleys' progressive social and intellectual milieu. It is divided into three series: Lesley's general correspondence, his correspondence with his brother Joseph, and microfilms of Lesley's research notes.